Price
Price is an especially important consideration for audio interfaces. The three most important purchases you can make as a musician/producer are your main instrument/controller, studio monitors, and audio interface. These are central to your workflow and its advisable to spend as much as you can reasonably afford.
Increased cost should either translate into a product with higher-value components or an expanded feature set. Now, while the latter is nice to have, there's no point paying for something you aren't going to use. A simpler interface at the same price point is probably packing better converters and preamps.
When selecting an audio interface, try to identify the features you can live without. This could be extra channels, specialised connections, or DSP. Then look at products in the upper bracket of your price range that only do the things that you need them to. These should provide the best value in terms of sound quality.